NMIMS Deemed-to-be University initially gained prominence by offering programs in Management, earning international recognition as a leading institution for management education. The Sunandan Divatia School of Science (SDSOS) was founded in 2007 with the aim of offering undergraduate and postgraduate students opportunities to pursue academic careers in the basic sciences. The school was established to foster a strong foundation in scientific disciplines, combining academic rigor with industry-relevant training, and preparing students for successful careers in science and research. Over the years, SDSOS has seen significant growth across multiple dimensions, including student enrollment and graduation rates, faculty recruitment and retention, research publications, patent registrations, and successful student placements in both academia and industry. In recent years, the school expanded its offerings by launching new undergraduate B.Sc. programs in cutting-edge fields like Data Science, Artificial Intelligence, Applied Psychology, Animation, and VFX.

As part of a strategic initiative, NMIMS leadership merged the School of Mathematical Sciences with the five programs from the Department of Statistics under SDSOS. This restructuring led to the creation of the Nilkamal School of Mathematics, Applied Statistics, and Analytics (NSOMASA), a new school dedicated to these evolving disciplines.